Splenomegaly is an enlargement of the spleen beyond its normal size. The spleen is an organ involved in the production and maintenance of red blood cells, the production of certain circulating white blood cells, and is a part of the lymph system and the immune system. Because of its wide variety of functions, the spleen may be affected by many conditions involving the blood or lymph system, and by infection, cancers, liver disease, and parasites.
Rupture of the enlarged spleen is particularly possible in infectious mononucleosis and several other causes of splenomegaly. Appropriate limitation of activity, including avoiding contact sports, will help prevent trauma that might cause the spleen to rupture. Care will be required for the specific condition causing the splenomegaly. Follow the instructions given by the doctor regarding appropriate care.