Sperm Count 50% Lower In Men Whose Fathers Smoke: Study
Men whose fathers smoked at the time of pregnancy had 50 per cent lower count of sperms than those with non-smoking fathers.
Research has not determined the underlying mechanisms behind smoking and sperm count
- Father's smoking is linked to shorter reproductive lifespan in daughters
- Smoking fathers can have various health outcomes in children
- The study was conducted on 104 Swedish men aged between 17 and 20 years
While studies have repeatedly linked maternal smoking during pregnancy with reduced sperm count in male children, a new research showed that men whose fathers smoked at the time of pregnancy also had 50 per cent lower count of sperms than those with non-smoking fathers.
The findings showed that, independently of nicotine exposure from the mother, socioeconomic factors, and their own smoking, men with fathers who smoked had a 41 per cent lower sperm concentration and 51 per cent fewer sperm count than those with non-smoking fathers.
"I was very surprised that regardless of the mother's level of exposure to nicotine, the sperm count of men whose fathers smoked was so much lower," said Jonatan Axelsson, specialist physician at Lund University in Sweden.
"We know there is a link between sperm count and chances of pregnancy, so that could affect the possibility for these men to have children in future.
"The father's smoking is also linked to a shorter reproductive lifespan in daughters, so the notion that everything depends on whether the mother smokes or not doesn't seem convincing," he added.
However, the research has not determined the underlying mechanisms behind this. But, similar studies have shown links between smoking fathers and various health outcomes in children, such as malformations, Axelsson noted.
It could be because most newly occurring mutations (known as de novo mutations) come via the father and there are also links between the father's age and a number of complex diseases, said researchers in the paper published in the journal PLOS ONE.
In addition, researchers have observed that smoking is linked to DNA damage in sperm and that smokers have more breaks in the DNA strand.
Children of fathers who smoke have been reported to have up to four times as many mutations in a certain repetitive part of the DNA as children of non-smoking fathers.
"Unlike the maternal ovum, the father's gametes divide continuously throughout life and mutations often occur at the precise moment of cell division.
"We know that tobacco smoke contains many substances that cause mutations so one can imagine that, at the time of conception, the gametes have undergone mutations and thereby pass on genes that result in reduced sperm quality in the male offspring," Axelsson said.
The study was conducted on 104 Swedish men aged between 17 and 20 years.
(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)
DoctorNDTV is the one stop site for all your health needs providing the most credible health information, health news and tips with expert advice on healthy living, diet plans, informative videos etc. You can get the most relevant and accurate info you need about health problems like diabetes, cancer, pregnancy, HIV and AIDS, weight loss and many other lifestyle diseases. We have a panel of over 350 experts who help us develop content by giving their valuable inputs and bringing to us the latest in the world of healthcare.