Adult children who have two parents with type 2 diabetes, but who are free from the disease themselves, have early signs of atherosclerosis.
![Children of diabetics have artery disease Children of diabetics have artery disease](https://drop.ndtv.com/images/story-noimage.png?q=50)
It was found that these individuals had arteries with reduced response to changes in blood flow, known as endothelial dysfunction, an early sign of atherosclerosis, sometimes referred to as hardening of the arteries. The average blood sugar levels were slightly higher in the group with a family history of diabetes, but within normal limits. However, those with a family history of diabetes showed a 38-percent lower arterial response than those with no family history of the disease. Even the most insulin-sensitive members of this group showed impaired arterial function.Above is the first study to demonstrate that modest increases in blood sugar, even in the non-diabetic range, can contribute to endothelial dysfunction. This raises the question of when doctors should recommend interventions to lower glucose levels and what should be the appropriate level of glucose recommended to patients with diabetes.
June 2006
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