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Testosterone helpful in heart failure

Treatment with the male hormone testosterone appears to improve exercise tolerance and reduce symptoms in men with heart failure, according to a small study. Larger studies are needed to verify these benefits and to clarify how the hormone works.

Testosterone helpful in heart failure

Treatment with the male hormone testosterone appears to improve exercise tolerance and reduce symptoms in men with heart failure, according to a small study. Larger studies are needed to verify these benefits and to clarify how the hormone works. Researchers form the Royal Hallamshire Hospital, UK, conducted a study with 20 men with heart failure who were given testosterone or inactive "placebo" injections every 2 weeks for 12 weeks. It was found that treatment with testosterone produced a significant improvement in the distance they could walk. Testosterone therapy also led to dramatic improvements in heart failure symptoms and may have had a beneficial effect on depression. None of these effects was seen with placebo. Treatment with the hormone had no major effect on muscle bulk and strength. Treatment with testosterone appeared to be safe and well tolerated, the researchers noted. However, one patient in the testosterone group did experience breathlessness after 8 weeks of therapy. Also a further study is needed in the filed to verify these benefits.

Heart,
April 2004

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