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Hep B vaccine protects for 15 years

After receiving three doses of hepatitis B vaccine, people are protected against infection for at least 15 years.

Hep B vaccine protects for 15 years

After receiving three doses of hepatitis B vaccine, people are protected against infection for at least 15 years. This finding argues against the need for booster doses of the vaccine. Hepatitis B virus can be transmitted through unprotected sex, injection drug use and being exposed to infected blood. The infection can be chronic and lead to liver damage and cancer. Previous reports have shown that hepatitis B vaccination provides protection for 10 years. However, the duration of protection beyond this period was unclear. Researchers from the from the Centers for Disease Control and Prevention in Atlanta, reviewed data on 1578 natives who were vaccinated at 6 months of age and older. Between 1981 and 1982, they received three doses of hepatitis B vaccine. In all age groups, hepatitis B vaccination strongly protected against infection for at least 15 years. The above findings argue against a need for booster doses of hepatitis B vaccine. Unless continued follow-up and surveillance show clinically significant rates of infection in adolescents or adults who were vaccinated as children, booster vaccinations will be wasteful.
Annals of Internal Medicine,
February 2005
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