Gold therapy helps in rheumatoid arthritis

Injecting gold in a liquid form of the metal can help people with rheumatoid arthritis. It can be effective when combined with another treatment. In a recent study, gold therapy reduced the severity of arthritis in patients who had a poor response with methotrexate, the standard drug used to treat the disease. Findings from several observation studies have shown that gold can augment the treatment response seen with methotrexate, but until now, this has not been investigated in a study in which patients were randomly selected to receive gold or inactive placebo injections. Researchers from the Arthritis Research Centre of Canada in Vancouver conducted a study involving 65 patients who received weekly injections of gold or placebo. At 48-week follow-up, significantly more gold-treated patients had experienced a treatment response than those given placebo. In addition, the gold therapy was found to me more cost-effective. These results support previous findings indicating that combination therapy with gold and methotrexate is useful when the latter agent fails to provide an optimal response. New and effective drugs called TNF blockers have recently become available for rheumatoid arthritis, but they are expensive. Given the high costs of newer anti-rheumatic drugs, there continues to be an important role for gold in combination with methotrexate, especially when cost is an issue.