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Antioxidants for a healthy skin

A cream containing vitamin C, vitamin E and ferulic acid protects the skin from sun damage and reduces cancer-associated mutations in skin cells.

Antioxidants for a healthy skin

A cream containing vitamin C, vitamin E and ferulic acid protects the skin from sun damage and reduces cancer-associated mutations in skin cells. Ultraviolet radiation damages the skin by causing oxidative stress. Previous studies have shown that vitamin C and vitamin E are individually effective in boosting antioxidant protection, and even more effective when used together and that ferulic acid, a plant antioxidant, increases the antioxidant effects of the vitamins even further. To find out whether or not topical applications of antioxidants help neutralise this damage, researchers from America tested the impact of a cream containing 15 percent vitamin C, 1 percent vitamin E, and 0.5 percent ferulic acid on human skin. They applied the cream to nine adults and then exposed them to simulated sun irradiation. It was found that compared to a cream with no active ingredients, the ferulic acid cream reduced skin redness after sun exposure and caused fewer skin cells to sunburn. The active cream almost completely blocked the production of thymine dimers, a type of UV-related genetic damage, as well as the induction of the tumor suppressor gene p53. Further, while unprotected skin exposed to UV radiation produced substances called cytokines that promote inflammation and suppress immune system function, protected skin did not. The above findings suggest that the antioxidant cream could be used as a supplement to sunscreen, providing maximal photoprotection of the skin.
Journal of the American Academy of Dermatology
September 2008

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