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Conditions misdiagnosed as bipolar disorder

A study suggested that bipolar disorder may be over-diagnosed in people seeking mental health care. Now new findings shed light on, which disorders many of these patients actually have.

Conditions misdiagnosed as bipolar disorder

A study published last year suggested that bipolar disorder may be over-diagnosed in people seeking mental health care. Now new findings shed light on, which disorders many of these patients actually have.

Bipolar disorder, also known as manic depression, involves dramatic swings in mood - ranging from debilitating depression to euphoric recklessness. In the original 2008 study, researchers found that of 145 American adults who said they had been diagnosed with bipolar disorder, 82 (57 percent) turned out not to have the condition when given a comprehensive diagnostic interview.

In the current study, researchers used similar standardised interviews to find out which disorders those 82 patients might have. Overall, they found, nearly half had major depression, while borderline personality disorder, post-traumatic stress disorder (PTSD), generalised anxiety and social phobia were each diagnosed in roughly one-quarter to one-third.

When the researchers then compared the patients with 528 other psychiatric patients who had never been diagnosed with bipolar disorder, they found that those in the former group were nearly four times more likely to have borderline personality disorder. They were also 70 percent more likely to have major depression and twice as likely to have PTSD.

Some of other diagnoses were less common but still seen at higher rates among the patients previously diagnosed with bipolar disorder. These included antisocial personality disorder and impulse-control disorder.

According to the researchers, over diagnosis of bipolar disorder is concerning, in part, because it is typically treated with mood-stabilising drugs that can have side effects - including effects on the kidneys, liver, and metabolic and immune systems. In addition, over diagnosis meant some patients are likely not getting the appropriate care for the problems they do have.

Bipolar disorder shares certain characteristics with some other psychiatric conditions. Borderline personality disorder, for instance, is marked by unstable mood, impulsive behaviour and problems maintaining relationships with other people. But researchers suspected that some doctors are over diagnosing bipolar disorder because - unlike certain other causes of mood disturbance - it does have effective drug therapies.

There are no medications approved specifically for treating borderline personality disorder, for instance, but research suggests that some forms of talk therapy are effective. The increased availability of medications that have been approved for the treatment of bipolar disorder might be influencing doctors who are unsure whether or not a patient has bipolar disorder or borderline personality disorder to err on the side of diagnosing the disorder that is treatable.
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