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Why drinking coffee cuts diabetes risk

Numerous studies have shown that coffee protects against type 2 diabetes. Yet no one has really understood why. Early studies have consistently shown an inverse association between coffee consumption and risk for type 2 diabetes, that is, the greater the consumption of coffee, the lesser the risk of diabetes.

Why drinking coffee cuts diabetes risk

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It was found that women who drank four cups of caffeinated coffee each day had significantly higher levels of SHBG than did non-drinkers and were half as likely to develop diabetes than were non-coffee drinkers. When the findings were adjusted for blood SHBG levels, the decrease in risk associated with coffee consumption was not significant, suggesting that it is SHBG that mediates the decrease in risk of developing type 2 diabetes.

Many clinical studies have revealed the important role of sex hormones in the development of type 2 diabetes, and it's known that SHBG not only regulates the sex hormones that are biologically active but may also bind to receptors in a variety of cells, directly mediating the signaling of sex hormones. The findings of this study suggest that SHBG in the blood does reflect a genetic susceptibility to developing type 2 diabetes and that this protein can be influenced by dietary factors such as coffee intake in affecting diabetes risk.
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