ASK OUR EXPERTS

Choose Topic
Using 0 of 1024 Possible characters
Home »  Cancer »  Breast Cancer Drug Linked To Brain Malfunction

Breast Cancer Drug Linked To Brain Malfunction

Breast cancer is the top cancer in women worldwide and is increasing particularly in developing countries where a majority of cases are diagnosed in late stages.

Breast Cancer Drug Linked To Brain Malfunction

Breast cancer is the top cancer in women worldwide.

HIGHLIGHTS

  1. A breast cancer drug reveals side-effects
  2. The drug letrozole is used to prevent breast cancer
  3. Breast cancer is the top cancer in women worldwide

A breast cancer drug reveals side-effects, including mood disturbances and memory issues, that impact the brain function in both humans and animals, say researchers. The drug letrozole is used to prevent breast cancer recurrence by interfering with the production of estrogens. For the study, researchers from the University of Toronto in Canada showed that they administered letrozole to male and female marmosets -- a nonhuman primate model -- for four weeks and observed many behavioural changes including hot flashes and increased anxiety, experienced by women receiving similar treatment.

In addition, letrozole also compromised the function of neurons in the hippocampus (organ located in the brain) and impaired spatial memory, results revealed, published in the Journal of Neuroscience.

Findings emphasise the need for further investigation of breast cancer treatments and their effects on the brain, the team noted.


Breast cancer is the top cancer in women worldwide and is increasing particularly in developing countries where a majority of cases are diagnosed in late stages.

nn1grds

A breast cancer drug reveals side-effects, including mood disturbances and memory issues, that impact the brain function in both humans and animals, say researchers. 
Photo Credit: iStock

COMMENT

DoctorNDTV is the one stop site for all your health needs providing the most credible health information, health news and tips with expert advice on healthy living, diet plans, informative videos etc. You can get the most relevant and accurate info you need about health problems like diabetes, cancer, pregnancy, HIV and AIDS, weight loss and many other lifestyle diseases. We have a panel of over 350 experts who help us develop content by giving their valuable inputs and bringing to us the latest in the world of healthcare.

................... Advertisement ...................

................... Advertisement ...................

FAQ

ASK OUR EXPERTS

Using 0 of 1024 Possible characters
Choose Topic

................... Advertisement ...................

-------------------------------- Advertisement -----------------------------------