Botox useful for leaky bladder

Treatment with Botox (botulinum-A toxin) can help women with urge incontinence, a type of urine leakage resulting from involuntary contractions of the bladder muscles. The treatment involves inserting a tube-like device called a cystoscope through the urinary opening into the bladder. Looking through the cystoscope, the doctor is able to inject the Botox directly into the hyperactive muscle, effectively eliminating the spasms. Researchers from the Duke University in Durham, North Carolina, USA, assessed the outcomes of seven women given a Botox injection for urge incontinence. The subjects were evaluated at several points up to 6 months after treatment. Aside from mild urinary tract infections in three patients, no side effects were noted in the participants. The incontinence and nearly all measures of urinary function improved significantly during follow-up, but after 6 months, most of the treated women seemed to be incontinent again, highlighting the fact that such therapy does not cure the condition. The results of the study suggest that Botox is a safe, effective therapy for the short-term management of severe urge incontinence. However, further studies are needed to confirm these findings and to address other issues, such as the dosage and how often Botox should be given.

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