The symptoms of the dreaded pre-menstrual syndrome (PMS) might be eased with the help of pheromones, chemicals present in all animals, including humans, which will be available in the form of nasal sprays. These chemicals, best known for their role in the mating behaviour of most animals, have been hypothesized to be helpful in alleviating some of the symptoms of PMS.
Research published in the recent issue of New Scientist suggests that human pheromones are powerful mediators of sexual attraction, anxiety and hormone related disorders. The human nose also contains a little known 'sixth sense' called the vomeronasal organ (VNO). This organ is able to detect small quantities of pheromones and sends a signal to the brain to bring about alleviation of PMS symptoms. Early nasal spray tests on 20 women showed decrease in symptoms like irritability, mood swings and breast pain in the participants.
The nasal spray being developed by a pharmaceutical company, Pherin Pharmaceutical Company in California, is said to contain a pheromone-like compound - Vomeropherin or PH80. This compound when inhaled, binds with receptors in the VNO and the nerve cells conduct the signal to the brain for reducing the symptoms. The researchers say that since this chemical has a direct link with the brain, the relief is immediate and lasts for about 2-4 hours.
Pheromones are chemicals naturally produced by the body of most animals which help them to sexually attract their partners for mating. These chemicals are also known to be ingredients of the body smell which is unique for every individual. Most people agree that they can recognise their dear ones with their unique body odour. If such naturally occurring chemicals can provide suggested relief, many women will heave a sigh of relief.
New Scientist, July 2001
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