Home » Frequently asked Questions on Health » Is it OK to take Mirtaz and Sulphitac for depression?

Is it OK to take Mirtaz and Sulphitac for depression?

Q: My mother is 45 years old and suffering from depression for the last one year. She recovered fully and medicines were also decreased. She was taking Mirtaz 7.5 at night. Now after 2 months there is a relapse. The doctor has prescribed Mirtaz 15 at night and Sulphitac in the morning. Are these medicines fine? I have read that Mirtaz has severe side effects. Is there another alternative? Her relapse is on alternate days i.e. she is completely fine one day and is depressed on the next. This has been going on for 2 weeks. What are the side effects of Sulphitac? There is no depression as of now. Does she need to take these medicines constantly? Will she get addicted to them?

A:Sulphitac is the brand name of a medicine called amisulpride. It is to be used only in patients of schizophrenia, not ordinary depression. The drug is not approved in the United States. Its side effects include: anxiety, agitation (very common) apart from sleepiness, constipation, nausea, vomiting and dry mouth. Other side effects include weight gain, acute dystonia (impairment of muscular tone), extrapyramidal side effects (such as involuntary movement of muscles), tardive dyskinesia (involuntary and painful spasm of neck muscles), low blood pressure, low heart rate and QT prolongation on ECG (which can be fatal if taken with other drugs that cause prolonged QT interval). Amisulpride can also lead to breast pain and end of menstrual cycle. Neuroleptic malignant syndrome is a rare though possible side effect. It is not clear as to why two potent medicines (with similar, additive side effects) are being given for depression, specially since she had responded to one medicine. Were usual medicines such as imipramine, amitriptyline, clomipramine, amoxapine given in the past? If not why was Mirtaz (mirtazapine) started? It should only be given when usual, conventional medicines are not effective. The side effects of Mirtaz include: worsening of depression, suicidal tendency, drowsiness, dizziness, sleepiness, nausea, dry mouth, constipation, asthenia, flu syndrome, headache. Raised liver enzymes, cholesterol, triglycerides. Oedema (retention of water), mania, bone marrow depression, jaundice: discontinue, fits, anxiety, agitation, myalgia (muscle pain), arthralgia (bone pain), malaise and blood disorders. It will be noticed that Mirtaz increases suicidal thinking. What about non-drug methods? Have you tried Yoga? Total dependence on drugs will mean not only more and more side effects but addiction.


................... Advertisement ...................




Using 0 of 1024 Possible characters
Choose Topic

Latest stories

Regional Cancer Centre Gets Clean Chit From Government-Appointed Panel

Wed, 20 Sep 2017 14:30:13 IST
Kerala Joint DME Sreekumari's team has given a clean-chit to the Regional Cancer Centre (RCC) with respect to the allegations that a 9-year-old girl patient who was admitted to the RCC, was given HIV-infected blood.

Swine Flu Explosion: 42 New Cases Reported In Mohali, Tips To Prevent It

Wed, 20 Sep 2017 13:30:42 IST
Mohali district reportedly sees increased number of cases of swine flu this year. So far, there have been 42 positive cases and five deaths of this deadly disease. Here's a list of tips to prevent it.

Angry With The Expensive Treatment, Patient Stabs The Doctor!

Wed, 20 Sep 2017 12:30:57 IST
When the doctor came in to examine him on Monday evening, the patient attacked the doctor in a fit of rage. It is being stated that the patient took this step because he was upset with the expensive treatment.

65 Year Old Zirakpur Man Dies Of Swine Flu

Wed, 20 Sep 2017 11:30:10 IST
A 65-year-old man, called Kirti Kumar died due to swine flu in Zirakpur, on Monday. This is the third swine-flu death in the Derabassi Subdivision within a period of one month.

Kerala AIDS Society Grants 'Clean Chit' To Regional Cancer Centre

Tue, 19 Sep 2017 15:30:10 IST
According to a report by the Kerala State AIDS Control Society, the blood given to a nine year-old girl during transfusion at Regional Cancer Centre (RCC) in Thiruvananthapuram was tested before the process, and HIV was not detected, but the same was detected at a later stage.