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Is it advisable to conceive after taking drugs for polycystic ovaries?

Q: I am a 29 years old woman with polycystic ovaries (PCOD) and hypothyroidism. My height is 5 feet and weight is 47 kg. My reports states USG - pelvis (screening); Uterus is retroverted retroflexed of normal size (7.1 x 4.1 x 3.7 cm) and echopattern. A small well defined, hypoechoic solid mass lesion of size 2.0 x 1.8 x 1.3 cm is seen at fundus posteriorly suggestive of myoma. Trilaminar regular endometrium of thickness 5.6 mm (8th day). The cervical endometrium is regular and well defined. Ovaries are bulky; right ovary measures 3.6 x 2.8 x 2.7 cm while left ovary measures 3.9 x 2.9 x 2.0 cm. Both ovaries show multiple small follicles suggestive of polycystic ovarian disorder. FSH 7.24 mIU/mL, LH 18.35 mIU/mL, androstenedione 2.57 mIU/mL, rubella IgG antibody 44.20 IU/mL, varicella zoster virus IgG 29.31 U/mL, T4 ferr 1.43 ng/dL, TSH 1.690 uIU/mL, Thyroid peroxidase antibody 75.60 U/mL, thyroglobulin antibody 50.30 U/mL. The doctor has advised me Diane – 35 and Thyronorm 50 for the last 2 years and but now I am not taking Diane- 35. Do these medicines have any side effects? Will I be able to conceive?

A:From your reports, it appears that you have polycystic ovaries with LH hypersecretion. However, you do not appear to be overweight. Diane is a good medicine and does not have any negative effects on happening of a pregnancy after it is stopped. However, LH levels are very high and you will have to take a high dose oral contraceptive pill. Retest LH if below 10 miu and then try for conception. Please consult a good infertility specialist.


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