Q: How should Nicotinell TTS nicotine patch be used and what are the side effects? Could you also let me know its cost, the duration of its use and if it is safe for women? Are their any variable strength patches? What are nicotine replacement products and the antidepressant drug Bupropion? What is the commercial name , so that I can get it from the chemist?

A:Nicotinell TTS are transdermal patches to be used over skin. It is available in three strengths: 17.5mg, 35mg, 52.5mg costing (without local taxes): 30 patches, Rs. 3043, Rs. 3175 and Rs. 3492 respectively. The dose depends on the smoking habit. For example, people who smoke more than 20 cigarettes a day will initially require 30cm-square patch every 24 hours; less than 20 cigarettes per day: 20cm-square patch every 24 hours. Maximum treatment period is 3 months though most people will need optimum treatment for 6-8 weeks and then half the dose for another 3-4 weeks. The patch has to be applied to a non-hairy area on trunk or upper arm. Smoking must be stopped when the treatment begins. Bupropion (Trade name: Zyban) is a oral tablet. It is used when the person is continuing to smoke. A target date for stopping smoking is set within the first 14 days. The cost is Rs. 400 for 10 tablets. The dose is: initially 1 tablet daily for 6 days to be increased to 1 tablet twice daily. Treatment is generally continued for 7-9 weeks. Treatment should be discontinued if there is no improvement by 7th week.