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What is the cause of unintentional weight loss?

Q: I lost about 51 pounds in 3 months. I cannot sleep, feel irritable and weak. My EOS percentage is 5.8. What should I do?

A:Unintentional weight loss is a decrease in body weight that is not voluntary and requires medical assessment if it is unexplained and more than 10% of normal body weight. The two basic mechanisms that lead to it are reduced intake of food or increased metabolic rate. Among the many causes are included endocrinal diseases (hyperthyroidism, diabetes, hyperparathyroidism, hypoadrenalism), gastrointestinal (malabsorption, chronic diarrhoea), psychiatric problems (eating disorders, depression, alcoholism), neurological diseases, chronic infections, cancer and medications. You need to be examined by a physician who will decide what investigations are necessary and then plan the treatment.

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