Q: My 29 years old wife has been suffering from rheumatoid arthritis (RA) for the last three years. She takes Oncotrex 5 mg as a dose of disease-modifying antirheumatic drugs (DMARD). Is this dose optimal for her?

A:No, this dose is not optimal at all. This is far below the actual effective dose of methotrexate, which is 20 to 25 mg once every week to be given as subcutaneous injections along with supplementation with folic acid - at least at the dose of 1 mg daily.

It is obvious that she is not being treated by an expert rheumatologist (specialist physicians trained in the evaluation, diagnosis and treatment of rheumatoid arthritis). I strongly recommend that you must immediately consult a rheumatologist so that she receives proper treatment of the disease.