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Can I use a substitute for my medicine for diabetes?

Q: Is the dosage of 2 mg Glypride equivalent to 5 mg Glyburide? I have run out of Glyburide and I am in a foreign country where I can only purchase Glypride 2 mg. I am supposed to take 10 mg Glyburide twice a day. Please suggest?

A:Glypride is NOT the chemical name of the medicine but it is a trade/brand name. It contains a medicine called glimepiride, which is used in diabetes. Glyburide is the chemical name of the medicine (not a trade name). In US it is called glyburide, while in rest of the world, including India, it is called glibenclamide popularly sold under the trade name of Daonil. You are currently on glibenclamide 5 mg (glyburide) twice daily. It is available all over the world. Please check with local chemist shop to know the brand name. You can also tell a friend/relative in India to send you Daonil by post. There are no restrictions. It would not be wise to replace medicines on your own.

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