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How to manage acute rejection of the kidney allograft?

Q: My kidney went into rejection after I forgot to take a medicine called Rapamune, for several days. The doctors are giving me prednisone and thybloglobic something? I am trying to avoid dialysis. Is there anything else that could be done?

A:Acute rejection of kidney allograft (transplanted kidney) is defined as the sudden worsening of the allograft function which is related to certain pathological changes in the parenchyma (body) of the kidney allograft. The standard treatment is based upon the allograft biopsy result which should be done immediately upon noticing the failure of the allograft since the results of the biopsy findings direct the common rescue therapy which involves high dosage of steroids besides other immune suppressive medications and immunomodulators. The treatment you are currently on is most likely based upon the aforementioned.


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