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How is linear morphoea treated?

Q: I am 22 years old and have linear morphoea from the past 13 to 14 years now. It is active and I have taken prednisolone foletrax folvite and dalvoni scalp solution yet unable to arrest the problem. My morphoea is still active and I don't know what to do, please suggest?

A:Linear morphoea (localised scleroderma) is normally not a serious disorder and burns out on its own in few years time. You have not given the size of the lesion and the speed at which it is increasing. Do you have just one lesion? Normally, one should use medicine for local application such as steroid creams/ointments on the scalp. Only in very severe cases it is necessary to use systemic (oral) drugs such as prednisolone. The oral dose of prednisolone (10 mg x 3 tabs on two days of the week) is too low and will have little effect. Larger doses may be effective but they can cause side effects. Have you tried steroid ointment locally, such as Betnovate? Other medicines that you have used are usually employed in severe, generalised morphoea. There are many and include: Topical calcipotril, methotrexate, systemic steroids, (such as prednisolone), Intralesional steroid injections, phototherapy with UVA1, Long courses of oral tetracycline antibiotics, cyclosporin, colchicine, Pentoxifylline, Penicillamine and Phenytoin.


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