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Can ACL surgery raise the risk of arthritis?

Q: After an ACL (anterior cruciate ligament) reconstruction what is the risk of osteoarthritis? If there is, then is there any prevention for this risk? I have read on Martha Murray's website that there is development of medicines for ACL healing. In that case can ACL reconstruction be avoided?

A:The goals of the ACL ligament surgery are to restore normal joint motion, return the patient to full function and prevent secondary injury and joint arthritis. There is no risk of developing OA knee. Knee pain probably is the most common and persistent complication after ACL reconstruction. The exact reasons are not known and several studies in the world literature have suggested a relationship between pain and knee flexion contracture or quadriceps weakness. I have also been aware of Martha Murray's website. They showed growth factors and scaffold substrate modification enhances cellular migration, proliferation, and collagen production by ACL cells in hopes of encouraging tissue regeneration and healing after ligament rupture. The comments, which I can make at this juncture is that the gel they found to be rebuilding ACL needs to be elaborated with open review, and perhaps and its needs accreditation. The other catch is that the authors may be biased because the football league committee funded it. Yes, there have been research and pilot studies over the future stem cell transplantation, which I think needs many trails before human use.


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