Q: I am a 29 years old female into my eighth week of pregnancy. My thyroid levels are FT3- 2.54, FT4 - 0.94, TSH - 1.44 and anti –TPO – 405. My endocrinologist has suggested Thyronorm 125 daily. I am taking Thyronorm 100 daily for the last one year. Will high thyroid levels affect pregnancy?

A:High antibodies in patients with hypothyoidism denote autoimmune process and cause of thyroid disease. High levels also mean that one will need treatment for a long time. Few observational studies have shown that high anti-TPO levels during first trimester are a risk for pregnancy fetal outcome. But this does not mean that every woman with high antibodies will have complications in their offspring. Increasing dose of Thyronorm in your case is a good decision. Please note there is no specific treatment to decrease the antibody levels.