What is the alternate medicine for Spiromide?

Q: What is the alternate medicine for Spiromide 40 mg if the male patient is having breast problems because of its prolonged use?

A:Spiromide is a combination product that contains two medicines: spironolactone and frusemide. It is the spironolactone ingredient that causes problems with male breast.There are many other effective diuretics such as metolazone (sold under the trade name of Metoz) 5-10 mg daily (maximum 80 mg daily) that can be employed in oedema due to heart impairment.