What are the adverse effects of overdosing of DPT and OPV?

Prof HPS Sachdeva
Prof HPS Sachdev,
Senior Consultant Pediatrics,
Sitaram Bhartia Institute of Science and Research,
New Delhi

Q: What are the side effects when vaccines like DPT and OPV are given more than the recommended dose?

A:Usually the recommended dose has very little chances of being exceeded. If it is exceeded in mild amounts, the fever and pain may be greater for DPT (whole cell killed vaccine) but nothing substantial for OPV.