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Is the combination of Norfloxacin with Tinidazole safe?

Dr Chandra M Gulhati
Editor, MIMS,
New Delhi

Q: What is the dose of suspension containing Norfloxacin 100 mg and Tinidazole 70 mg/5ml for children?

A:The fixed-dose combination of norfloxacin with tinidazole is irrational.Such a combination is not allowed to be sold in any country other than India. Norfloxacin is an antibacterial while tinidazole is anti-amoebic. A correct diagnosis of the disease should be made and appropriate medicine should be prescribed. A combination of this nature renders bacteria, such as typhoid, resistant which can be life-threatening.