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Is it safe to take Nizonide-O in ulcerative colitis?

Dr Chandra M Gulhati
Editor, MIMS,
New Delhi

Q: I am a 33 years old man weighing 74 kg. I take these medicines – Azaron (100 mg), Wyasolone (40 mg) and Mesacol 1.2-1.2-1.2 gm per day. Is it safe to take Nizonide-O in ulcerative colitis?

A:Nizonide-O is an irrational combination of two drugs: nitazoxanide (used in amoebiasis) and ofloxacin (antibacterial). It has no role in ulcerative colitis. Such a combination is not permitted in any advanced country.