How can kidney rejection be prevented in transplantation?

Q: I am a 25 years old boy who has undergone kidney transplantation 8 years back. The new kidney has been rejected. Now I have to go for re-transplantation. What are the things to be kept in mind so that my new kidney does not get rejected again?

A:You should look for a better matched kidney, which usually happens to be a sibling or parents to provide better long term survival of the graft. Nowadays induction agents like ATG or Il2receptor antibody like Simulect are used along with Tacrolimus to reduce the chances of rejection. A regular follow up and monitoring for complications and early diagnosis and treatment all help to improve outcomes in the transplant.