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Does a progesterone capsule work better orally or vaginally?

Dr Geeta Chadha
Senior Consultant, Obstetrics & Gynaecology,
Indraprastha Apollo Hospital,
New Delhi

Q: I want to know how the gelatin capsule, progesterone will be helpful when used through vaginal insertion? If we take the medicine orally, will it mix in the blood to help cure the disease or not? What is a better route - oral or vaginal?

A:Even the vaginal insertion works via blood absorption, however the local uterine action is better.