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Can Metoclopramide be taken through the rectal route in pregnancy?

Dr Chandra M Gulhati
Editor, MIMS,
New Delhi

Q: Can Metoclopramide be taken through the rectal route for vomiting during the 8th week of pregnancy without any risks.

A:Route of administration is not important because ultimately the medicine reaches the blood. The safety of metoclopramide during pregnancy has not been established; hence it should not be used.