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Metabolic syndrome predicts kidney disease

Type 2 diabetics with metabolic syndrome have a higher risk of developing chronic kidney disease.

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Type 2 diabetics with metabolic syndrome have a higher risk of developing chronic kidney disease. Metabolic syndrome refers to a cluster of risk factors for diabetes and heart disease -- including abdominal obesity, high blood pressure, high blood sugar, low levels of "good" HDL cholesterol and high triglycerides. The syndrome is typically diagnosed when a person has three or more of these conditions.To explore the association between metabolic syndrome and its components and kidney disease, researchers from China followed 6,445 Hong Kong Chinese with type 2 diabetes. It was found that the risk of developing chronic kidney disease increased as the number of components of the metabolic syndrome increased. Further, patients with four components of the metabolic syndrome were twice more likely to have chronic kidney disease, while those with five components had at a three-fold higher risk of kidney disease. It was noted that the presence of metabolic syndrome was associated with a 31 percent higher risk of kidney disease compared with people with no evidence of metabolic syndrome.The above findings suggest that conventional cardiovascular risk factors are also predictors of kidney disease and thus, doctors should actively assess patients with diabetes for these risk factors and treat them aggressively.
American Journal of Epidemiology
December 2008

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