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Q&A
If you have any query about any medical problem get an answer from an expert

Does alcohol affect SGPT and SGOT levels?

Thursday, 08 July 2010
Answered by: Dr Sanjiv Saigal
Consultant Gastroenterologist,Sir Ganga Ram Hospital,New Delhi

Q. I am a 31 years old male weighing 93 kg. I was diagnosed with abdominal tuberculosis 15 months back. After taking medicines for a year, I have recovered from tuberculosis. But for the last three months, my SGPT & SGOT level started fluctuating. I smoke also. My doctor has suggested me to take Ursodeoxycholic (500 mg) for three months. I took it for a month, after that my SGPT level came to normal. So, I stopped taking prescribed medication, but now my SGPT and SGOT level has been increasing. How can it be treated? Moreover, two years back, I used to be a regular drinker, drinking 2-3 pegs daily. My HCV test came negative.

A.  I note that you have been treated for abdominal tuberculosis recently. Now your concern is that you have raised SGOT & SGPT. As your abdominal tuberculosis treatment has been stopped a year back, it is unlikely that you have drug-induced hepatotoxicity. As you consume alcohol regularly, it is possible that it may be the cause of your deranged LFT. In addition, I note that you are overweight, which can also affect your liver. You need a thorough evaluation to find out the cause of your liver problem including an ultrasound, viral hepatitis markers, autoimmune markers, etc. You must stop alcohol, and can continue taking UDCA meanwhile.

A.  I note that you have been treated for abdominal tuberculosis recently. Now your concern is that you have raised SGOT & SGPT. As your abdominal tuberculosis treatment has been stopped a year back, it is unlikely that you have drug-induced hepatotoxicity. As you consume alcohol regularly, it is possible that it may be the cause of your deranged LFT. In addition, I note that you are overweight, which can also affect your liver. You need a thorough evaluation to find out the cause of your liver problem including an ultrasound, viral hepatitis markers, autoimmune markers, etc. You must stop alcohol, and can continue taking UDCA meanwhile.

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