ASK OUR EXPERTS

Choose Topic
Using 0 of 1024 Possible characters
Home »  News »  Low-dose aspirin affects kidneys

Low-dose aspirin affects kidneys

Many people take a low dose of aspirin daily to help ward off heart trouble, but there could be a down side to it. Low-dose aspirin therapy may have a "significant adverse effect on renal function" in elderly patients, as reported by researchers.

Low-dose aspirin affects kidneys

Many people take a low dose of aspirin daily to help ward off heart trouble, but there could be a down side to it. Low-dose aspirin therapy may adversely affect the kidneys in elderly patients. Although low-dose aspirin is used by many elderly patients, monitoring of kidney function is currently not recommended as a routine. Researchers at the Tel Aviv Medical Center, Israel recently reported transitory retention of uric acid and creatinine that are signs of kidney impairment caused by aspirin at doses of 75 to 325 milligrams per day. To investigate further, they examined the effects of 100 mg of aspirin taken daily for two weeks by 83 stable geriatric patients (who averaged 81 years of age), and compared them with 40 similar control patients. The researchers collected blood samples, and examined 24-hour urine collections for creatinine and uric acid, at baseline and weekly for 5 weeks. Urinary excretion of creatinine decreased in 60 (72 percent) of patients and excretion of uric acid decreased in 54 (65 percent) after 2 weeks of aspirin therapy. Average clearance of uric acid also decreased in these patients. The deterioration in kidney function was significantly greater (and more prevalent) in the aspirin-treated group than in the 40 control patients. They found that kidney function improved after aspirin was stopped, but even three weeks later 48 percent of the patients still had some residual impairment. Physicians are well aware of the possible adverse effects of non-steroidal anti-inflammatory drugs and high-dose aspirin on the kidneys. More attention should be paid to the effects of low dose aspirin, especially in the elderly.

American Journal of Medicine, October, 2003
Low-dose aspirin aspirin kidneys
Was this Article Helpful Yes or No

................... Advertisement ...................

Q&A

ASK OUR EXPERTS

Using 0 of 1024 Possible characters
Choose Topic

Latest stories

GST: Your Private Health Care Costs Might Increase

Thu, 22 Jun 2017 18:37:21 IST
Even though healthcare and education is not included in the GST raise, the price of the drugs, equipments and AP's will experience an escalation.

Olive Oil Can Help Preserve Memory And Prevent Alzheimer's

Thu, 22 Jun 2017 15:58:03 IST
Olive oil, a key ingredient of the Mediterranean diet and a healthier medium of cooking than regular oil can also preserve memory and prevent Alzheimer's disease, new study says.

5 Pre-menopause Symptoms Every Woman Should Know

Thu, 22 Jun 2017 17:15:07 IST
Menopause marks the end of your fertility period, it's when your biological clock chimes time up. Here are a few symptoms to identify early signs of menopause.

Hyderabad Raid Shows What Happens To Surrogate Mothers Post-delivery

Thu, 22 Jun 2017 16:45:37 IST
Legal and medical aides are provided to the surrogate mothers but much of it remains on paper only. The health conditions of surrogate mothers can deteriorate if they don't receive timely medical and sanitary facilities.

Eating Fish Can Help Treat Arthritis: Study

Thu, 22 Jun 2017 12:46:15 IST
Fish along with having a lot other health benefits, is also a rich source of Omega-3s acid which is believed to lessen the effect of Rheumatoid Arthritis.