----------------------- Advertisement --------------------------
Q&A
If you have any query about any medical problem get an answer from an expert
  Comments: Read | Post

What are SGOT and SGPT?

Friday, 12 November 2010
Answered by: Dr Venk Mani
Consultant Gastro-enterologist Physician, Leigh Infirmary, England
Google Buzz

Q. I am a 31 years old male having Serum glutamic oxaloacetic transaminase (SGOT) – 200 and Serum glutamic pyruvic transaminase (SGPT) – 195. What are SGOT and SGPT? What causes increase in SGOT and SGPT levels?

A.  Both SGOT and SGPT are enzymes produced by liver cells of which SGPT is very much liver specific. When the liver cells get damaged these enzymes get released and their levels in the blood go high. As for instance, in case of viral infection of the liver called Hepatitis, the levels can be very high due to cell damage and by monitoring them regularly the doctor can assess the severity as well as the improvement or deterioration. This ofcourse has to be taken into account as with other tests and investigations. SGPT on the other hand can be produced by cells from other parts. This in a nutshell is the answer to your question and if your enzymes are persistently high further investigations are indicated. Finally, both the enzymes SGOT and SGPT were re-named over two decades ago and are now known as ALT and AST.

A.  Both SGOT and SGPT are enzymes produced by liver cells of which SGPT is very much liver specific. When the liver cells get damaged these enzymes get released and their levels in the blood go high. As for instance, in case of viral infection of the liver called Hepatitis, the levels can be very high due to cell damage and by monitoring them regularly the doctor can assess the severity as well as the improvement or deterioration. This ofcourse has to be taken into account as with other tests and investigations. SGPT on the other hand can be produced by cells from other parts. This in a nutshell is the answer to your question and if your enzymes are persistently high further investigations are indicated. Finally, both the enzymes SGOT and SGPT were re-named over two decades ago and are now known as ALT and AST.

Comments: Read | Post
More from this section
More »
Post comments
We request you not to tell us about your medical problems through this comment tool.
We are unable to keep track of the innumerable queries and their answers that we get everyday unless they are sent through "Ask a Question"

Name:*   E-mail:*
City:   Phone:
Comments:* 7000 characters remaining
Spam protection
Enter the code:*
Disclaimer: Material sent in this section is contributed by users. DoctorNDTV accepts no responsibility for the content or accuracy of such material and does not endorse or subscribe to the content.
----------------------- Advertisement4 --------------------------
 
Latest Photos
 
 
Survey
Radiation and health outcomes

The effect radiation has on human health has been the subject of recent interest.

-------------------------------- Advertisement -----------------------------------