A.  A few studies have shown that normal TSH is around 2.5 only but this has not been accepted for definition of hypothyroidism. Keeping this in mind you become a case for starting treatment with Thyroxine sp if your anti-TPO is positive. It is not true that patient with subclinical hypothyroidism (as you are) are resistant to weight loss. Usually, with hypothyroidism there is weight gain, which is around a few kg, and this disappears after treatment. I hope you are not taking snacks in between your meals or excessive tea or coffee. The other option is that you might have to go for a medical treatment of obesity using Sibutramine or so. This is likely to help you.