A.  1. To assess breathlessness, please get a stress echocardiography done to check the status of your heart. Also get a lipid profile done. It is very important for you to keep your cholesterol under control 2. Avoid constipation. Use a stool softener like lactulose (duphalac) daily so that you pass semi-formed rather than hard stools. Also local ointments maybe used for rectal bleeding. Avoid spicy foods and nuts 3. Erectile dysfunction may sometimes be a component of diabetes. See a urologist who can evaluate you and prescribe medication like sildenafil if needed 4. Get your glycosylated haemoglobin blood test done to see whether your overall sugar control is adequate or not. 5. There are medicines available to lose weight. Otherwise your prescription of medicines looks ok. Consult your doctor and he can add these other medicines for you.