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A.
Pan Graf is the brand name; the name of the medicine is tacrolimus. Similarly Myfortic brand contains mycophenolic acid. Blood tacrolimus levels should remain between 5 to 15 nanogram/mL; thus a level of 8.7 is within the acceptable range. Unless it increases rapidly and starts touching 15nanogram/mL, the current dose appears to be rational. With regard to Myfortic (mycophenolic acid), the internationally recommended and accepted dose is 720mg twice daily. There is no mention of thrice daily schedule in any clinical trial. In any case overdose, even if given, does not cause toxicity. Normally we use Wysolone (prednisolone), which is a steroid, in kidney transplant cases. A dose of 20mg is quite rational. There is no advantage in replacing one tried-and-tested steroid with another steroid. Moreover deflazacort (Defcort) is not in vogue for kidney transplant patients. One should alter medicines when clearly clinically required. In short: prima facie the current dose appears to be quite rational. It is absolutely essential to ensure that transplant does not get rejected.
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