A.  I notice that you have non-alcoholic cirrhosis and that your medication for under active thyroid is not working. Cirrhosis of the liver produces new liver cells, which continue as immature cells and unfortunately are not very effective in taking over the functions of the healthy cells. In several instances, non-alcoholic cirrhosis has an auto-immune basis, which essentially means a condition where a chronic inflammatory process in the body targets one or more organs in the body. You could well have this auto-immune basis to your cirrhosis, where your thyroid gland has also got affected besides the liver. The treatment to be effective one needs to suppress the auto-immune mechanism by using the drugs called steroids alongside your thyroxin supplement. There are several tests, which can be done to prove auto-immune disorder and I advise you to consult a specialist immunologist for proper investigations and treatment.