----------------------- Advertisement --------------------------
Q&A
If you have any query about any medical problem get an answer from an expert
  Comments: Read | Post

Nephrotic syndrome in children

Wednesday, 18 April 2001
Answered by: Dr. Rekha Agrawal
Associate Prof. Paediatrics
Director Paediatric Nephrology
Loyola University Medical Center
Illinois
Google Buzz

Q. My son of 3.5 years was having swollen limbs and especially penis & scrotum. It was detected as Nephrotic Syndrome, which was confirmed after tests. He was hospitalised for 15 days. Before this he only had mild cough & cold for 10-15 days. Right now he is taking Prednisolone 10mgx2 and Distaclor 5mlx3. My question is, what precaution we should take to avoid repeated attack of this? What is your advise about food etc? Any specific suggestion? How harmful is this disease on the long-term health of the kidney?

A.  Nephrotic syndrome in a young child like your son generally responds well to prednisone( 80-90% )and the urine protein goes away. In about 20% it may not come back, but in the rest, protein starts reappearing in urine, often triggered by an infection eg. a cold. There is no way of preventing this, either by diet or any other measure. We advise these children to lead normal lives. We teach all the parents to learn to test the urine at home for protein, using dipsticks, initially about 3-4 times a week, daily if the child has an infection. If protein comes back and stays for more than 3-4 days, we often treat with prednisone, usually for just a few days, since the disease relapse is picked up early, before the child gets swollen. Fruits are good for your child, I do not know why you are avoiding them. We advise salt restriction. In most children there is no underlying cause for the Nephrotic syndrome. For unknown reasons, the charges on the kidney change, making the kidney pores bigger so that protein leaks out in the urine. Prednisone closes the pores stopping the leakage of protein. If your child needs prednisone constantly or gets protein in the urine more than 3 times a year, you might talk to your physician about other medications. Also if your child has never had chickenpox or received the chickenpox vaccine, then each time he comes in contact with a child with chickenpox, you should call your pediatrician for protective treatment. I would advise a blood test for chicken pox antibodies to see if your child has natural immunity against chicken pox.

A.  Nephrotic syndrome in a young child like your son generally responds well to prednisone( 80-90% )and the urine protein goes away. In about 20% it may not come back, but in the rest, protein starts reappearing in urine, often triggered by an infection eg. a cold. There is no way of preventing this, either by diet or any other measure. We advise these children to lead normal lives. We teach all the parents to learn to test the urine at home for protein, using dipsticks, initially about 3-4 times a week, daily if the child has an infection. If protein comes back and stays for more than 3-4 days, we often treat with prednisone, usually for just a few days, since the disease relapse is picked up early, before the child gets swollen. Fruits are good for your child, I do not know why you are avoiding them. We advise salt restriction. In most children there is no underlying cause for the Nephrotic syndrome. For unknown reasons, the charges on the kidney change, making the kidney pores bigger so that protein leaks out in the urine. Prednisone closes the pores stopping the leakage of protein. If your child needs prednisone constantly or gets protein in the urine more than 3 times a year, you might talk to your physician about other medications. Also if your child has never had chickenpox or received the chickenpox vaccine, then each time he comes in contact with a child with chickenpox, you should call your pediatrician for protective treatment. I would advise a blood test for chicken pox antibodies to see if your child has natural immunity against chicken pox.

Comments: Read | Post
More from this section
More ยป
Post comments
We request you not to tell us about your medical problems through this comment tool.
We are unable to keep track of the innumerable queries and their answers that we get everyday unless they are sent through "Ask a Question"

Name:*   E-mail:*
City:   Phone:
Comments:* 7000 characters remaining
Spam protection
Enter the code:*
Disclaimer: Material sent in this section is contributed by users. DoctorNDTV accepts no responsibility for the content or accuracy of such material and does not endorse or subscribe to the content.
----------------------- Advertisement4 --------------------------
 
Latest Photos
 
 
Survey
Radiation and health outcomes

The effect radiation has on human health has been the subject of recent interest.

-------------------------------- Advertisement -----------------------------------