Q&A
If you have any query about any medical problem get an answer from an expert
  Comments: Read | Post

What is my glomerular filtration rate (GFR)?

Friday, 17 March 2006
Answered by: Dr. Ashutosh Singh
Consultant Nephrologist
Knoxville,
USA
Google Buzz

Q. I am 27 years old and have a creatinine level of 1.1. My weight is 87 kgs. I wanted to know if my glomerular filtration rate is less or it is fine? Is their any intervention required?

A.  Chronic kidney disease (CKD) is indeed an unrecognised problem in India with a potential to acquire an epidemic proportion. Glomerular Filtration Rate (GFR) is accepted as a best overall measure of one’s kidney function both in healthy and diseased state. GFR is estimated from a prediction equation that takes into account not only the serum creatinine but also some other variables that include age, gender, race and body size. CKD can be staged from Stage 1 to 5 based on an estimated GFR value with stage 5 reflecting a low GFR, associated with advanced kidney disease. Studies from the sub-continent have shown that the normal GFR value for a healthy Indian adult appears to be much lower than that accepted for a western population. The mean GFR value of a young healthy Indian adult is 81.4 ± 19.4 ml/min/1.73 m2 body surface area, which is significantly different from the normal value of 109-125 ml/min for a western population. CKD could also be diagnosed in someone who may have normal GFR value but have kidney damage for at least 3 months reflected by its markers including abnormalities in the composition of urine or an abnormal renal imaging test. Based on the information you provided, your approximate estimated GFR is 85 ml/min/body surface area which would be considered within the normal range. Moreover, if you do not have the risk factors for CKD namely, a history of diabetes, hypertension or a family history of either of these, you should not be required to undertake any intervention.

A.  Chronic kidney disease (CKD) is indeed an unrecognised problem in India with a potential to acquire an epidemic proportion. Glomerular Filtration Rate (GFR) is accepted as a best overall measure of one’s kidney function both in healthy and diseased state. GFR is estimated from a prediction equation that takes into account not only the serum creatinine but also some other variables that include age, gender, race and body size. CKD can be staged from Stage 1 to 5 based on an estimated GFR value with stage 5 reflecting a low GFR, associated with advanced kidney disease. Studies from the sub-continent have shown that the normal GFR value for a healthy Indian adult appears to be much lower than that accepted for a western population. The mean GFR value of a young healthy Indian adult is 81.4 ± 19.4 ml/min/1.73 m2 body surface area, which is significantly different from the normal value of 109-125 ml/min for a western population. CKD could also be diagnosed in someone who may have normal GFR value but have kidney damage for at least 3 months reflected by its markers including abnormalities in the composition of urine or an abnormal renal imaging test. Based on the information you provided, your approximate estimated GFR is 85 ml/min/body surface area which would be considered within the normal range. Moreover, if you do not have the risk factors for CKD namely, a history of diabetes, hypertension or a family history of either of these, you should not be required to undertake any intervention.

Comments: Read | Post
More from this section
More »
Post comments
We request you not to tell us about your medical problems through this comment tool.
We are unable to keep track of the innumerable queries and their answers that we get everyday unless they are sent through "Ask a Question"

Name:*   E-mail:*
City:   Phone:
Comments:* 7000 characters remaining
Spam protection
Enter the code:*
Disclaimer: Material sent in this section is contributed by users. DoctorNDTV accepts no responsibility for the content or accuracy of such material and does not endorse or subscribe to the content.
----------------------- Advertisement --------------------------
 
Latest Photos
 
Search Cloud
 
Poll
Q. Is cord blood banking just a money-making gimmick?
Yes No
Post your comment | Previous poll  
 
Survey
The Superbug and India?
The Superbug and India?
Do you think it is justified to advise UK patients against coming to India for surgery based on a single report in a medical journal?
Join survey »
 
Bouquets & Brickbats
Thanks for the help
Sent by priyankar sarkar 
More »
-------------------------------- Advertisement -----------------------------------