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Cancer - Undifferentiated carcinoma

Wednesday, 13 June 2001
Answered by: Dr. N. Nayak
Senior Consultant and Head Dept. of Histopathology
Sir Ganga Ram Hospital
New Delhi.
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Q. My 36 year old cousin is suffering from undifferentiated carcinoma. Please give details about the problem and the possible line of treatment.

A.  Carcinoma is a malignant tumour (cancer) of glandular cells (cells in the lining surfaces of the body). A carcinoma is said to be "undifferentiated" when the tumour cells have no resemblance at all to normal glandular or surface lining cells. Such "undifferentiated" cancers are generally more aggressive than "differentiated" ones. The response to treatment and long term effects are however dependent on the treatment given and sometimes on the exact site of the cancer. In case of breast carcinoma, the treatment given generally is wide removal of the tumour or the whole breast (depending on the size of tumour) and a follow-up by chemotherapy or radiotherapy. Some of these tumours are known to respond well to proper treatment given well in time.

A.  Carcinoma is a malignant tumour (cancer) of glandular cells (cells in the lining surfaces of the body). A carcinoma is said to be "undifferentiated" when the tumour cells have no resemblance at all to normal glandular or surface lining cells. Such "undifferentiated" cancers are generally more aggressive than "differentiated" ones. The response to treatment and long term effects are however dependent on the treatment given and sometimes on the exact site of the cancer. In case of breast carcinoma, the treatment given generally is wide removal of the tumour or the whole breast (depending on the size of tumour) and a follow-up by chemotherapy or radiotherapy. Some of these tumours are known to respond well to proper treatment given well in time.

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