----------------------- Advertisement --------------------------
Q&A
If you have any query about any medical problem get an answer from an expert
  Comments: Read | Post

What is the reason for high Ig E level in the blood?

Wednesday, 19 March 2008
Answered by: Dr. Shirish Kumar
Consultant Haematologist,
Sir Ganga Ram Hospital,
New Delhi
Google Buzz

Q. What is the indication of high Ig E level in the blood?

A.  I am not sure what you exactly mean by indication of IgE level. I suppose you mean the reasons for it and perhaps the clinical manifestations of such a state. Immunoglobulin E (IgE) is an antibody, which is specifically related to allergy and its levels go up in blood (and tissues) in allergic conditions. But measuring total IgE levels in blood is not very specific as this value can be raised in parasitic infections, immunologic disorders, some cancers (myeloma, Hodgkin's disease) and even smoking or consuming alcohol. A normal IgE level does not exclude significant allergic disease. The most common causes are allergic disorders (skin, respiratory tract, drugs), parasitic infestations, immunologic disorders, certain infections etc. The IgE antibody is classically associated with what is called the Type I hypersensitivity reaction. In case of systemic reaction (called anaphylaxis) caused by drugs, toxins, venoms, blood products etc., the symptoms are severe and life threatening. These include severe breathing problem, circulatory collapse and swelling of body. A food allergy presents with vomiting, diarrhoea and skin reactions. Other allergic disorders like hay fever or asthma have symptoms specific to the organ involved.

A.  I am not sure what you exactly mean by indication of IgE level. I suppose you mean the reasons for it and perhaps the clinical manifestations of such a state. Immunoglobulin E (IgE) is an antibody, which is specifically related to allergy and its levels go up in blood (and tissues) in allergic conditions. But measuring total IgE levels in blood is not very specific as this value can be raised in parasitic infections, immunologic disorders, some cancers (myeloma, Hodgkin's disease) and even smoking or consuming alcohol. A normal IgE level does not exclude significant allergic disease. The most common causes are allergic disorders (skin, respiratory tract, drugs), parasitic infestations, immunologic disorders, certain infections etc. The IgE antibody is classically associated with what is called the Type I hypersensitivity reaction. In case of systemic reaction (called anaphylaxis) caused by drugs, toxins, venoms, blood products etc., the symptoms are severe and life threatening. These include severe breathing problem, circulatory collapse and swelling of body. A food allergy presents with vomiting, diarrhoea and skin reactions. Other allergic disorders like hay fever or asthma have symptoms specific to the organ involved.

Comments: Read | Post
More from this section
More ยป
Post comments
We request you not to tell us about your medical problems through this comment tool.
We are unable to keep track of the innumerable queries and their answers that we get everyday unless they are sent through "Ask a Question"

Name:*   E-mail:*
City:   Phone:
Comments:* 7000 characters remaining
Spam protection
Enter the code:*
Disclaimer: Material sent in this section is contributed by users. DoctorNDTV accepts no responsibility for the content or accuracy of such material and does not endorse or subscribe to the content.
----------------------- Advertisement4 --------------------------
 
Latest Photos
 
 
Survey
Radiation and health outcomes

The effect radiation has on human health has been the subject of recent interest.

-------------------------------- Advertisement -----------------------------------