| Profile |
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 | | Dr Narinder Mehra | Head of Dept. of Histocompatibility and Immunogenetics,
AIIMS, New Delhi
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Born: November 4, 1949 in Amritsar, Punjab (INDIA).
Activities:
- Head of the Department of Histocompatibility and Immunogenetics, AIIMS.
- Secretary-General, Federation of Immunological Societies of Asia-Oceania (FIMSA),(1992- 2000).
- President, Indian Immunology Society,(1998-2000).
- President, Australasian & South East Asian Tissue Typing Association (ASEATTA),(1998-99).
- President, 6th Asia-Oceania Histocompatibility Workshop (6AOH).
- Visiting Professor at -
- Academisch Ziekenhuis Leiden, Holland
- Bir Hospital, Kathmandu.
- Siriraj Hospital Bangkok, Thailand Council Member, International Union of Immunological Societies (1992-95)
- Honorary consultant, Armed Forces Medical Services for Transplantation Immunology
- Vice President, Federation of Immunological Societies of Asia-Oceania (FIMSA) (2000-2003).
Awards and Honours:
- H.J. Mehta Gold Medal (1977)
- IRA-Boots’ Gold Medal and Oration (1983)
- Shakuntala Amir Chand Prize of ICMR (1983)
- Prof. E. Moses Gold Medal and Oration by RSSDI (1984)
- INSA Research Fellow (1986)
- S.S. Bhatnagar Award of the CSIR (1995)
- Sher-I-Kashmir Sheikh Mohammed Abdullah Award (1995)
- Ranbaxy Research Foundation Award (1996)
- Prof G.S. Randhawa Oration (1996)
- Fellow, National Academy of Sciences, Allahabad (1998)
- JALMA Trust Foundation Award of ICMR (1999)
Academic Duties:
- Member, Scientific Advisory Committee of the Central JALMA Institute for Leprosy, Agra.
- Member, DBT Task Force on Human Genetics and Human Genome Analysis.
- Member, ICMR Task Force on Human Genetics.
- Reviewer for Research Projects from various national and international funding agencies.
Editorial Duties:
- Reviewer for international journals - Lancet, Human Immunology, Scandinavian Journal of Rheumatology.
- Member, International Advisory Board of the Asian Pacific Journal of Allergy and Immunology.
- Member, International Editorial Board of APLAR Journal of Rheumatology (Singapore).
- Member, International Editorial Board of Gulf Medical College Health Journal.
- Regional Editor of Microbes and Infection (Institut Pasteur, Paris)
- Guest Editor for special issue of Human Immunology.
- Reviewer for other journals-Ind J. Med Res, Ind. J Nephrology.
- Member, International Advisory Board of Modern Rheumatology (Japan).
Academic Fellowships:
- International Medical Sciences Academy, New Delhi (1987)
- North Eastern Academy of Molecular Biology and Genetics FNMG (1993)
- National Academy of Sciences, Allahabad, F.N.A.Sc (1998)
Books:
- Basic methods in HLA-DNA technology. Technical manual published during the DBT sponsored training workshop on HLA-DNA technology, December 1989, eds. Mehra NK, Sagar publishers, New Delhi.
- Molecular Technologies for HLA Testing: Focus on donor selection during transplantation. Fine Pinters, New Delhi, eds. N.K. Mehra, January 1996.
- Scientific and technical aspects of HLA. eds. Mehra NK (in preparation).
Thesis Guided - 20 Ph.Ds, 5DM/MCh, 19 MD/MS, 3MSc
Publications: Total 253
Topics of Interest:
- Histocompatibility and Immunogenetics - Identification of HLA linked susceptibility parameters in various diseases.
- Identification of HLA gene products at the molecular level. RFLPs and PCR-oligotyping using SSOPs.
- Molecular basis of susceptibility to infectious and autoimmune diseases.
- HLA matching and immunological factors in organ and bone marrow transplantation.
Positions held in Relation to Immunology/Immunogenetics:
- Secretary, Asia Oceania Network for creation of Federation of Immunology (1990-1993)
- Secretary, INSA National Committee of Immunology (1991-1994)
- Secretary, Indian Immunology Society (1990-92)
- Councilatory' from India in several International Histocompatibility Workshops. He has made several original contributions in mycobacterial, autoimmune and rheumatological diseases that have helped greatly in understanding the molecular basis of susceptibility to these diseases.
- His studies in the transplantation context have revealed that in situations involving live related donor renal transplantation, HLA matching has an overriding influence in long term graft survival. Further, he has identified important immunological predictors for graft rejection, which include quantitation of interleukin-2 receptors, IgG anti-F(ab)2g antibodies and TNF alpha levels. Further importance of flowcytometric crossmatches and regular screening of anti-leukocyte antibodies in the recipient both at the pre as well as post transplant stages has been highlighted in his studies.
- He has established the Asian Indian Donor Marrow Registry (AIDMR) of voluntary unrelated donors for patients of Asian Indian origin requiring bone marrow transplantation. This registry has already recruited more than 2000 voluntary donors, most of whom are tested for both HLA class I as well as class II genes. The AIDMR has developed functional links with similar international registries which include the National Marrow Donor Program (NMDP) of USA and the Bone Marrow Donors World Wide (BMDW) of Europe.
- Professor Mehra has several international recognitions which include the prestigious `Council Membership' of the International Union of Immunological Societies (IUIS). He is the founder Secretary General of the Federation of Immunological Societies of Asia-Oceania (FIMSA), Vice President of the 10th International Congress of Immunology, New Delhi, (Nov. 1998), President of the Asia-Oceania Histocompatibility Federation, President of the Australasian and South East Asian Tissue Typing Association (ASEATTA) and President of the Indian Immunology Society.
- In 1992, he was awarded the S.S.
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